Francesca Fiorelli
Phd Student in Clinical Physiopathology - Academic Year 2018-2019
Curriculum: Cardiopulmonary
Research project: Cardiogenic shock and rapidly deteriorating heart failure requiring mechanical circulatory support devices: integrated approach from pathophysiology to clinical outcome.
Supervisor: Prof. Anna Petronio
The use of temporary mechanical circulatory support (MCS) devices has increased dramatically over the last few years in patients presenting with cardiogenic shock (CS), however evidence regarding its impact on outcomes is still lacking and controversial. The aim of the study is to investigate in patients in CS supported by MCS, the four key aspects of the “haemodynamic support equation” (systemic perfusion, ventricular unloading, venous decongestion, and coronary perfusion) looking for correlation with overall survival. A targeted management of pharmacological and mechanical support in these critically ill patients should positively impact outcomes.
Scientific Articles
- COAPT-Like profile predicts long-term outcomes in patients with secondary mitral regurgitation undergoing MitraClip implantation. Adamo M, Fiorelli F, Melica B, D'Ortona R, Lupi L, Giannini C, Silva G, Fiorina C, Branca L, Chiari E, Chizzola G, Spontoni P, Espada Guerreiro C, Curello S, Petronio AS, Metra M. JACC Cardiovasc Interv. 2021 Jan 11;14(1):15-25
- MitraClip in secondary mitral regurgitation as a bridge to heart transplantation: 1-year outcomes from the International MitraBridge Registry. Godino C, Munafò A, Scotti A, Estévez-Loureiro R, Portolés Hernández A, Arzamendi D, Fernández Peregrina E, Taramasso M, Fam NP, Ho EC, Asgar A, Vitrella G, Raineri C, Adamo M, Fiorina C, Montalto C, Fraccaro C, Giannini C, Fiorelli F, Popolo Rubbio A, Ooms JF, Compagnone M, Maffeo D, Bettari L, Fürholz M, Tamburino C, Petronio AS, Grasso C, Agricola E, Van Mieghem NM, Tarantini G, Curello S, Praz F, Pascual I, Potena L, Colombo A, Maisano F, Metra M, Margonato A, Crimi G, Saia F. J Heart Lung Transplant. 2020 Sep 17: S1053-2498(20)31745-9
- Impact of disproportionate secondary mitral regurgitation in patients undergoing edge-to-edge percutaneous mitral valve repair. Adamo M, Cani DS, Gavazzoni M, Taramasso M, Lupi L, Fiorelli F, Giannini C, Branca L, Zuber M, Curello S, Petronio AS, Maisano F, Metra M EuroIntervention. 2020 Aug 28;16(5):413-420
- Five-year clinical outcomes after percutaneous edge-to-edge mitral valve repair: insights from the multicenter GRASP-IT registry. M. Adamo, C. Grasso, D Capodanno, A. P Rubbio, S. Scandura, C. Giannini, F. Fiorelli, C. Fiorina, L. Branca, N. Brambilla, F. Bedogni, A.S. Petronio, S. Curello, C. Tamburino Am Heart J. 2019 Nov;217:32-41
Seminars, symposiums, conferences
- Non-contrast CT scan for the evaluation of the aortic annulus and low-contrast TAVI: results from a small case series of patients with severe chronic renal failure. M. Angelillis, G. Costa, C. Giannini, M. De Carlo, P. Spontoni, F. Fiorelli, A. Pieroni, A.S. Petronio. EuroPCR Congress 2019 (Poster presentation)
- Five-year clinical outcomes after edge-to-edge mitral valve repair by MitraClip system: insights from the GRASP-IT registry. M. Adamo, C. Grasso, A. Popolo Rubbio, C. Giannini, F. Fiorelli, C. Fiorina, F. Bedogni, A.S. Petronio, S. Curello, C. Tamburino. EuroPCR Congress 2019 (Oral presentation)
- Evaluation of a Novel Method Using Computed Tomography For Predict New Onset of Atrial Fibrillation or Embolic Events after Transcatheter Aortic Valve Implantation: Role of Hounsfield Unit Density Ratio in the Left Atrial Appendage M. Angelillis, G. Costa, R. Antonazzo Panico, C. Giannini, F. Fiorelli, P. Spontoni, L. Stazzoni, M. De Carlo, A.S. Petronio TCT 2018 (Oral presentation)
Contacts
- francesca.fiorelli@phd.unipi.it